Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1209 | 1209c | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 21 |
| 2 | 3TC+D4T+EFV | 36 |
| 3 | 3TC+AZT+NFV | 21 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62AV | K103N | P225H | I135V, D177G, I178M, R211K, V245K |
| >1209c| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPGMVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTP DKKHQKEHPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14KR, M36MI, N37S, R41RK, L63P |
| >1209c| codons 6-99 WQRPLVTVRIGGQLKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQIPIE ICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |