Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0308 | 0308b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+D4T | 7 |
| 2 | Unknown | 51 |
| 3 | D4T+DDI+EFV | 25 |
| 4 | 3TC+D4T+EFV | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V108I | I37X, S48T, K122Q, I135L, T139A, I142T, S162A, D177G, V179I, R211K |
| >0308b| codons 37-247 VCTEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLKKNKSVTILDVGDAYFSVPLDQDFRKYTAFTIPSLNNEAPGTRYQYNVLPQGWKGS PAIFQASMTKILEPFRKQNPGIIIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTT PDKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K20R, L33V, L63Q, I64V |
| >0308b| codons 4-99 TLWQRPLVTIKIGGQLREALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYDQIQ VEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |