Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0983 | 0983b | U.S. | 1999 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 43 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K20T, E35D, M36I, R41K, R57K, H69K, L89M, I93M |
| >0983b| codons 4-99 TLWQRPVVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T39A, E44D, V60I, D121H, K122E, D123S, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211K |
| >0983b| codons 38-247 CAEMEKDGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLHESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRSKNPEIIIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |