Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BREPM11948 | BREPM11948 | Brazil | 1999 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, E35D, M36I, R41K, R57K, Q61N, L63C, C67D, T74S, V77I, L89M |
| >BREPM11948| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NICIEIDGHKAIGSVLIGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, D123E, I135T, I202V, E248D, A272P, K277R, K281R, A288S, E297K, V317A, Q334L, V365I, A376T, T377M, T386I, E399D, A400T, K431T, R463K, V466A, D471E, T477A, H483Q, L491S, S519N, K527N, A534S, V559I |
| >BREPM11948| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKSLTEVIPLTKEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARMRGA HTNDIKQLTEAVQKITMESIVIWGKIPKFKLPIQKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPIVGAETFYVDGAANRETKLGKAGYVTDRGKQKAVSLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKVYLSWVPAHK GIGGNEQVDKLVSAGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, L28I, V32I, I72V, V77A, I84L, L101I, S119P, T124A, T125A, K136Q, V201I, D207N, K211N, Y227F, L234V, D256E | S283G |
| >BREPM11948| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNIPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAAHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGPN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATNIQTNELQKQITKIQNFRVYFRDSRDPVWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| de Sa Filho, DJ | Identification of two HIV type 1 circulating recombinant forms in Brazil. | ARHR, 2006 |