Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UGA08483 | 99UGA08483 | Uganda | 1999 | HIV1 | D | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| M50L, I72V, L101I, T112I, I113V, T124A, T125A, I135V, F181L, V201I, Y227F, L234I, A265V |
| >99UGA08483| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEALHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKIVHTDNGSN FTSAAVKAACWWAGVKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV LIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, Q18H, N37S, R41K, I64V |
| >99UGA08483| codons 1-99 PQITLWQRPLVTVKIGGHLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, K122E, D123G, I135V, E169D, D177E, I178M, I195R, G196E, T200I, Q207G, R211K, V245T, D250E, A272P, L282C, L283I, T286A, I293V, A327V, G335D, P345Q, F346H, R356K, A360T, T377Q, S379C, K390R, A400T, V458I, S468P, L469I, H483N, S519N, A534S, A554N, V559I | G285R |
| >99UGA08483| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEMVI YQYMDDLYVGSDLEREQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKCIRRAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQDQWTYQIYQEQHKNLKTGKYAKMRGT HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYITDRGRQKVVPITDTTNQKTELQ AINLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKIL |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |