<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
0908MO 01CM.0908 Cameroon 2001 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, I72V, G82S, T112V, I113V, T124A, T125A, K156N, E157Q, V201I, L234I, D256E V281M, S283G
>01CM.0908| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASSYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNNQLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCMAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, L63P, H69Q  
>01CM.0908| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, E36D, K49R, V60I, K103R, D123E, K173I, Q174K, D177E, Q207E, P243A, V245Q, E248D, A272P, K277R, Q278H, T286A, E291D, I293V, E297A, L303M, I329V, Q334H, G335D, F346H, R356K, M357R, G359T, K366R, A371V, A376S, T386I, K390R, A400T, K431T, V435A, D471E, H483Y, L491S, Q509H, S519N, Q524H, K527Q, A534S, A554S  
>01CM.0908| codons 1-560
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTDVVPLTAEAE
LEMAENREILKEPVHGVYYDPSKDLIAEVQKQGHDQWTYQIYQEPHKNLKTGKYAKRRTA
HTNDVRQLTEVVQKISTESIVIWGKIPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELQ
AIYLALQDSGSEVNIVTDSQYALGIIQAHPDKSESELVNQIIEHLIQKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Kijak, GH Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. ARHR, 2004