Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1918LE | 02CM.1918 | Cameroon | 2002 | HIV1 | CRF25_cpx | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19I, K20I, E35D, M36I, R41K, Q61E, L63V, I64L, C67S, H69K, V82I, L89I |
| >02CM.1918| codons 1-99 PQITLWQRPLVTVKIGGQIIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD EIVLEISGKKAIGTVLVGPTPINIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39N, E40D, K49R, V60I, T107S, D123E, I135T, S163T, E169G, P170T, K173A, Q174K, D177E, Q207E, R211K, V245K, K275Q, K277R, T286A, E291D, V292I, I293V, E297V, E312N, D324E, I329V, Q334D, F346Y, R356K, M357G, R358G, G359S, T369A, E370A, S379G, T386I, K390R, A400T, E404D, V435I, K454R, D471E, Q480H, L491S, L517I, S519N, A534S, A554N |
| >02CM.1918| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSTMTKILGTFRAKNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDIVPLTVEAE LELAENREILKNPVHGVYYDPSKELIAEVQKQGDGQWTYQIYQEPYKNLKTGKYAKGGSA HTNDVKQLAAAVQKIATEGIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGRAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, M50L, T112V, I113V, S119P, T124A, T125A, G163T, D167E, V201I, T206S, T218I, L234I, D256E | S283G |
| >02CM.1918| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEALHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGPN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIITQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |