<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
0130NY 01CM.0130 Cameroon 2001 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, A21T, A23V, D41N, M50I, I72V, T112V, S119T, T124A, T125A, G134D, K136Q, D167E, V201I, Y227F, L234I, S255N S283G, D288N
>01CM.0130| codons 1-288
FLDGIDKAQEDHERYHSNWRTMVSDFNLPPVVAKEIVASCNKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGTN
FTSAAVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNNDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, N37D, R41K, H69K, I72R, L89M  
>01CM.0130| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKARGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I5V, K11T, V35T, T39K, D121Y, K122E, D123G, I135T, S162C, E169D, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q, E248D, D250Q, A272Q, V276I, T286A, E312N, G335D, M357R, G359S, E370Q, A371V, I375V, S379G, K390R, T403M, K431R, E432D, A446S, D471E, T477A, Q480H, H483Y, L491S, K512R, L517S, S519N, Q520L, Q524K, K527E, A534S, A554S  
>01CM.0130| codons 1-560
PISPVETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPEIVI
YQYMDDLYVGSDLEIEQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKQSWTVNDIQKLVGKLNWASQIYQGIKIKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVKQLTQVVQKVATEGIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLERDPIVGAETFYVDGASNRETKLGKAGYVTDRGRQKVVSLTETTNQKAELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESESVNLIIEKLIEKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Kijak, GH Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. ARHR, 2004