<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
0001BBY 01CM.0001 Cameroon 2001 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, A21T, A23V, V31I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134E, K136Q, V165I, D167E, V201I, L234I, D270E S283G, D288N
>01CM.0001| codons 1-288
FLDGIDKAQEDHERYHSNWRTMVSDFNLPPIVAKEIVASCNKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWAEIQQEFGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIREYGKQMAGDDCVAGRQDEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, N37D, R41K, H69K, L89M  
>01CM.0001| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11A, V21I, V35T, T39K, V60I, D121Y, K122E, D123G, I135T, K166R, E169D, K173A, Q174K, D177E, G196E, T200I, E203D, Q207A, R211S, V245Q, E248N, K277R, T286A, I293V, K311R, G335D, M357K, G359S, A371V, I375V, S379G, K390R, T403M, E432D, V435I, N447S, D471E, T473I, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, A534S, A554S, V559I  
>01CM.0001| codons 1-560
PISPIETVPVALKPGMDGPKIKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILDPFRAKNPEIVI
YQYMDDLYVGSDLEIEQHRIKIDELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVKQLTEVVQKVATEGIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETINQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNLIIEKLIEKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKIL

References
Author Title Citation
Kijak, GH Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. ARHR, 2004