Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 4412HAL | 01CM.4412 | Cameroon | 2001 | HIV1 | D | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6S, K7E, E10D, E11D, E13D, V31I, V32I, I72V, A91S, T112V, I113V, T124A, T125A, K156N, E157Q, V201I, T218S, N222H, L234I |
| >01CM.4412| codons 1-288 FLDGISEAQDDHDKYHSNWRAMASDFNLPPIIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPSETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNNQLKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQISKIQHFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, R41K, L63P, H69Q |
| >01CM.4412| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V21I, V35T, E36D, T39K, K49R, V60I, D123E, I135T, S162C, R172K, D177E, I178L, V179I, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, K277R, T286A, V292I, E297K, R307K, V317A, I329V, Q334D, Y339W, G359S, K390R, E399D, T403M, V435I, A446S, E449D, R461K, L469F, D471N, H483N, L491A, E492K, L517I, S519N, A554S | Q182S |
| >01CM.4412| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTDICKEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFKKQNPELII YSYMDDLYVGSDLEIGQHRAKIEKLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIIPLTKEAE LELAENKEILKEPVHGAYYDPSKDLIAEVQKQGDGQWTWQIYQEPFKNLKTGKYARMRSA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWDAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGASNRDTKLGKAGYVTDKGRQKVVSFTNTTNQKTELQ AINLALQDSGAKVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |