<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
1710LE 02CM.1710 Cameroon 2002 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134N, D167E, V201I, T218I, L234I, K236R, D256E, R262K S283G
>02CM.1710| codons 1-288
FLDGIDKAQEDHEKYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWRGPAK
LLWKGEGAVVIQDNSEIKVVPKRKAKIIRDYGKQMAGDDCVAGRQDED

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        D17N, V35T, E36D, T39L, M41I, E42K, W71*, K122E, D123N, K166R, E169K, F171Y, R172K, K173T, Q174K, D177E, T200E, E204D, V245K, E248D, D250E, A272P, K275Q, T286A, E291D, V292I, I293V, E297A, I329V, Q334L, G335D, R356K, M357R, G359T, K366R, T369A, A371V, T377L, K390R, K395R, E396D, A400T, E404D, V435I, E449D, L452I, R461K, S468T, D471E, Q480E, E529D, A534S, A554S  
>02CM.1710| codons 1-560
PISPIETVPVKLKPGMNGPKVKQWPLTEEKIKALTDICLEIKKEGKISKIGPENPYNTPV
FAIKKKDSTK*RKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILKPYKTKNPEIVI
YQYMDDLYVGSDLEIGQHREKIEDLRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPDKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDVRQLAEVVQKIALESIVIWGKTPKFRLPIQRDTWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRDTKIGKAGYVTDKGRQKVVTLTETTNQKTELE
AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Kijak, GH Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. ARHR, 2004