Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 3228MN | 02CM.3228 | Cameroon | 2002 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, R20K, L28I, V31I, V32I, T93I, L101I, T112V, T124A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, A265V | S283G |
| >02CM.3228| codons 1-288 FLDGIDKAQEEHERYHSNWKAMASDFNIPPIIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAEIGQETAYFILKLAGRWPVKVIHTDNGSN FTSATVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12K, I13V, K14R, G17E, K20I, M36I, R41K, H69K, L89M |
| >02CM.3228| codons 1-99 PQITLWQRPLVKVRIGEQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, V35T, E36D, T39L, I135V, S162A, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207E, P243H, V245Q, V276I, T286A, E291D, I293V, S322T, G335D, R356K, M357K, G359S, I375V, T377M, K390R, K395R, T403M, E432D, R461K, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S |
| >02CM.3228| codons 1-560 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICLEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPYRTKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQHIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDVVPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEAVQKVAMESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |