Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 0190MA | 01CM.0190 | Cameroon | 2001 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35G, M36I, R41K, H69K, V77L, L89M |
| >01CM.0190| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLLGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, T39R, K104R, K122E, D123G, T139M, S162A, K173T, Q174K, D177E, V179I, T200A, Q207E, R211K, F214L, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, E297D, S322A, L325I, R356K, M357K, G359S, T369A, E370D, A371V, K374R, I375V, A376T, K390R, A400T, T403M, E432D, V435I, S468P, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N, K558R |
| >01CM.0190| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNEMPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIII YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTDEAE LELAENREILKEPVHGVYYDPAKDIIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLADVVQRVTTESIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSNGIRRVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L68I | E11D, K14R, V31I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, T218I, L234I | S283G, D288N |
| >01CM.0190| codons 1-288 FLDGIDKAQEDHERYHSNWRAMASDFNLPPIVAKEIVASCNKCQLKGEAIHGQVDCSPGI WQLDCTHIEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDEN |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |