<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2339SA 02CM.2339 Cameroon 2002 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    V31I, I72V, E96D, T112V, T124A, T125A, V126M, G134N, K136Q, V201I, L234I S283G
>02CM.2339| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQDTAYFLLKLAGRWPVKVIHTDNGSN
FTSAAMKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, M36I, R41K, K43R, I64L, H69K, K70R, V82I, L89M  
>02CM.2339| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QILLEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, E36D, T39M, V60I, K122E, I135V, S162A, K173T, Q174K, D177E, G196E, T200A, Q207E, V245Q, K281R, E291D, V292I, I293V, P294T, E312D, S322A, I326V, G335D, F346Y, R356K, M357K, G359S, K366R, T369A, A371V, I375V, A376S, A400T, T403V, W410Y, E432D, V435A, A446S, L452M, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N  
>02CM.2339| codons 1-560
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTDICMEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIEQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPYKNLKTGKYAKKRSA
HTNDVRQLAEVVQKVSTESIVIWGKTPKFKLPIQKETWETWWVEYWQATYIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFYVDGASNRETKMGKAGYVTDRGRQKVVSLTETTNQKTELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Kijak, GH Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. ARHR, 2004