Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 4410HAL | 01CM.4410 | Cameroon | 2001 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, D25E, E35Q, S39N, L101I, T112V, T124A, T125A, G134D, I135V, K136T, K188R, V201I, T206S, T218I, L234I, R269K | S283G |
| >01CM.4410| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASEFNLPPVVAKQIVANCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWADVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRRGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, L19P, K20I, M36I, R41K, L63S, H69K, L89M |
| >01CM.4410| codons 1-99 PQITLWQRPLVTVRIGGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39A, V60I, K122E, I135L, S162A, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357R, G359S, A371V, I375V, K390R, K395R, T403M, V417A, E432D, G436E, D471E, Q480H, H483L, L491S, K512R, L517A, S519N, Q524K, K527E, E529D, A534S, A554S |
| >01CM.4410| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEMVI YQYMDDLYVGSDLEIGQHRAKIEKLREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFANTP PLVKLWYQLEKDPIVEAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AILLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEAVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |