Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1970LE | 02CM.1970 | Cameroon | 2002 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| T97A | K14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, R269K | S283G |
| >02CM.1970| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQEAAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, M36I, R41K, H69K, L89M |
| >02CM.1970| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39S, D123E, I135T, S162A, F171Y, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245E, A272P, T286A, E291D, V292I, I293V, P294T, Q334L, G335D, R356K, M357R, G359T, A371V, I375V, T377I, K390R, K395R, T403M, E432D, V435L, R461K, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S |
| >02CM.1970| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICSEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPYRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEVVQKVAIESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPILGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Kijak, GH | Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. | ARHR, 2004 |