Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1411 | 99CM.1411 | Cameroon | 1999 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| T97A | V31I, L63M, I72V, L74I, T112V, I113L, T124N, T125A, V126M, G134N, K136Q, D167E, V201I, I203M, T218S, L234I | L158LF |
| >99CM.1411| codons 1-249 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQMDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQEAAYFLLKLAGRWPVKVLHTDNGSN FTSNAMKAACWWANIQQEFGIPYNPQSQGVVESMNKEFKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQISKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, G16E, M36I, R41K, H69K, I72V, L89M |
| >99CM.1411| codons 1-99 PQITLWQRPVVTVRIEGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6S, V8I, V35T, T39N, I50V, K122E, D123S, A158S, K173A, D177E, G196E, T200A, Q207A, R211S, V245Q, E248D, A272P, T286A, E291D, I293V, E297R, A304E, E312D, I326V, G335D, Y342F, M357K, R358K, G359S, K366R, A371V, I375V, A376AT, T377L, K390R, E432D, V435A, N447S, R448K, E449D, L452Q, S468I, T470N, D471E, Q480H, H483Y, L491S, Q509T, K512R, L517I, S519N, Q524E, K527R, K530R, V531I, A534S, A554Q |
| >99CM.1411| codons 1-560 PISPISTIPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKVGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIEQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVPLTREAE LELEENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIFQEPFKNLKTGKYARKKSA HTNDVRQLTEVVQKVTLESIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAASKDTKQGKAGYVTDRGRQKVVILNETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQATPDRSESEIVNQIIEELIRKERIYLSWVPAHK GIGGNEQVDKLVSQGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |