Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP640 | 97CM.640 | Cameroon | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L74LM | K14R, S24N, K34R, I72V, L101I, G106A, T112I, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, T218S, Q221H, N222K, L234I |
| >97CM.640| codons 1-249 FLDGIDKAQEEHERYHSNWRAMANDFNLPPVVAREIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVIMVAVHVASGYIEAEVIPAETGQETAYFILKLAARWPVKIVHTDNGSN FTSAAVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQISKIHKFRVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, E35D, M36I, R41K, R57K, H69K, L89M |
| >97CM.640| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K122E, D123N, K166R, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q, E248D, K277R, L283I, I293V, P294T, E312D, G335D, M357K, R358K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, E399D, A400T, T403M, E404D, E432D, T470N, D471E, Q480H, H483L, L491S, S519N, Q524K, K527G, E529D, V531I, A534S, A554S |
| >97CM.640| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRSQNPEIII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGTKALTEVVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKKSA HTNDVRQLAEVVQKVVMESIVIWGKTPKFKLPIQKETWDTWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLNETTNQKTELH AILLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEKLIGKDKIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |