Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1033 | 98CM.1033 | Cameroon | 1998 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, Y99L, L101I, T112M, T124A, T125A, G134N, K136T, V201I, L234I |
| >98CM.1033| codons 1-249 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETALFILKLAGRWPVKMIHTDNGSN FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89M |
| >98CM.1033| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V179E | V21I, V35T, K43R, S48E, V60I, K173T, Q174R, D177G, T200A, Q207E, V245Q, E248D, D250E, S251N, A272P, V276I, T286A, E291D, V292I, I293V, E297A, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, I375V, Q394R, E396D, A400V, E404D, E413D, Q428R, K431T, V435A, F440Y, A446S, R461K, R463K, V466I, V467I, S468T, D471E, H483Q, L491S, S519N, A534S, A554N |
| >98CM.1033| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEREGKIEKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPGIEI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLTEVVQKVATESIVIWGKTPKFKLPIRKDTWEVWWTDYWQATWIPDWEFVNTP PLVKLWYRLETEPIAGAETYYVDGASNRETKLGKAGYVTDKGKQKIITLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |