Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1371 | 99CM.1371 | Cameroon | 1999 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, L28I, V32I, M50I, L74I, L101I, T112V, T124A, T125A, G134D, I135V, K136T, V201I, T206S, L234I |
| >99CM.1371| codons 1-248 FLDGIDKAQEDHERYHSNWRAMASDFNIPPVIAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIIIVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWADVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, I15L, K20I, E34A, M36I, N37S, R41K, H69K, V77I, L89M |
| >99CM.1371| codons 1-99 PQITLWQRPVVTVKLGGQLIEALLDTGADDTVLAEISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, E40D, V60I, K103Q, K104R, D121H, K122E, I135R, I142T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, K275R, K281R, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, A376V, K390R, A400T, E432D, V435I, D471E, K476R, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N, K558R, V559I |
| >99CM.1371| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKQRSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSRNNETPGTRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIRVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA HTNDVKQLVEVVQKVVTESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQRTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSNGIRRIL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |