Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1014 | 98CM.1014 | Cameroon | 1998 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, K215N, T218I, L234I |
| >98CM.1014| codons 1-249 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQNQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, I64M, H69K, L89M |
| >98CM.1014| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39K, K43E, K122E, D123S, I135T, S162C, K173S, D177E, V179I, T200I, Q207A, V245M, A272P, K281R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410H, N418S, E432D, R448K, D471E, Q480H, L491S, E492T, S515L, L517I, S519N, Q524K, K527E, A534S, A554N |
| >98CM.1014| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSQNPEIII YQYMDDLYVGSDLEIGQHRIKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLVEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWMEYWQATHIPEWEFVSTP PLVKLWYQLEKDPIVGAETFYVDGAANKETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSTVNIVTDSQYALGIIQAQPDKSELEIVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |