Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1417 | 99CM.1417 | Cameroon | 1999 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L74M | K14R, V31I, L101I, T112I, T122TI, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234I | L242LH |
| >99CM.1417| codons 1-249 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIIMVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKIIHTDNGSN FISAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIASDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK LHWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M |
| >99CM.1417| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E40D, A98S, K122E, D123S, T165I, K173T, Q174K, T200A, I202V, Q207E, V245Q, E248D, D250E, S251D, A272P, T286A, E291D, V292I, I293V, E297A, E312N, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371T, A376C, T386I, Q394R, A400I, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, Q480H, H483Q, L491S, K512R, S519N, A534S, A554S |
| >99CM.1417| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKVEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKNPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLTETVQKICTESIVIWGKIPKFKLPIRKETWEIWWTEYWQATWIPDWEFVNTP PLVKLWYRLETEPIAGAETYYVDGAANRETKLGKAGYVTDKGKQKIITLTETTNQKTELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |