Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP1433 | 99CM.1433 | Cameroon | 1999 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, S24N, M50I, T112I, I113V, T124N, T125A, K136Q, D167E, V201I, R224Q, L234I |
| >99CM.1433| codons 1-249 FLDGIDKAQEDHEKYHSNWRAMANDFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIVHTDNGSN FTSNAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFQVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89M |
| >99CM.1433| codons 1-99 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4T, K11T, V35T, T39K, D121C, K122E, S162C, K173S, Q174K, D177E, Q207E, R211K, V245Q, E248D, A272S, K281R, E291D, V292I, I293V, E312N, I326V, G335D, M357K, G359S, K366R, T369A, I375V, T377Q, K395R, A400T, T403M, E432D, V435A, V458I, R461K, V467I, D471E, Q480H, L491P, K512R, S515A, S519N, Q524K, K527E, A534S, A554S |
| >99CM.1433| codons 1-560 PISTIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL CEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSKNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGTKALTDIVPLTEEAE LELAENREILKNPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLAEAVQKVAQESIVIWGKTPKFKLPIQRETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYITDKGRQKVISLTETTNQKTELH AIHLALQDSGPEVNIVTDSQYALGIIQAQPDRSEAELVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |