Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MP812 | 97CM.812 | Cameroon | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, A21T, V31I, I72V, K111R, T112V, T124A, T125A, G134N, K136Q, I162V, D167E, V201I, L234I |
| >97CM.812| codons 1-249 FLDGIDKAQEDHERYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRVIHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIVGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, N37E, R41K, H69K, L89M |
| >97CM.812| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDIELPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, T39N, K122E, D123S, K173A, D177E, T200I, Q207A, R211S, V245L, T286TA, E291D, I293V, P294T, E312D, D324E, G335CS, M357Q, G359S, T369V, A371V, I375V, S379G, K388T, T403R, E404D, E432D, V435A, D471E, Q480H, H483N, L491P, K512R, L517I, S519N, Q524K, K527G, K530R, A534S, A554S | Y146YC |
| >97CM.812| codons 1-560 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQCNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPILLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKDPVHGVYYDPSKELIAEIQKQGQSQWTYQIYQEPFKNLKTGKYARQRSA HTNDVKQLVEVVQKVATEGIVIWGKTPTFKLPIQKETWEAWWRDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AINLALQDSGPEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIGKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Njai, HF | The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | Retrovirology, 2006 |