Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CB471 | CB471 | Cuba | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, S57N, L101I, T112V, S119P, T124A, T125A, G134S, K136T, V201I, A205S, T206S, L234I, S255N, D256E | S283G |
| >CB471| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCNPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN FTSAAVKAACWWASITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIISSDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M |
| >CB471| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, S162C, D177E, I195L, G196E, T200A, R211K, V245M, D250E, E297A, D324E, R358K, G359N, T377Q, T403M, V435E, R463K, V466I, A554N |
| >CB471| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLELEQHRAKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKNA HTNDVKQLTEAVQKIAQESIVIWGKTPKFKLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIEGAETFYVDGAANRETKLGKAGYVTDRGKQKIVSLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Sierra, M | Identification of 3 phylogenetically related HIV-1 BG intersubtype circulating recombinant forms in Cuba. | JAIDS, 2007 |