<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KL007 05_007.1 Malaysia 2005 HIV1 CRF01_AE PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, V31I, V37A, S39N, L63V, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I208L, L234I, D279G Q62R, T97I
>05_007.1| codons 1-288
FLDGIDKAQEEHERYHSNWRTMASDFNLPPIVAKEIAANCDKCQLKGEAMHGQVDCSPGI
WRVDCTHLEGKVILVAVHVASGYIEAEVIPAETGQEIAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDLQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDGCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, H69K, K70R, L89M  
>05_007.1| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35I, S68G, K122E, K173I, Q174K, D177E, I178M, T200I, Q207A, R211N, K238R, V245E, R284K, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357R, G359S, K366R, A371V, K390R, K395R, W398R, A400T, T403M, E432D, V435I, N447S, R461K, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, Q547K, A554S  
>05_007.1| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETRETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAASRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVNQIIEELIKKEKVYLSWVPAHK
GIGGNEKVDKLVSSGIRKVL

References
Author Title Citation
Tee, KK Identification of a novel circulating recombinant form (CRF33_01B) disseminating widely among various risk populations in Kuala Lumpur, Malaysia. JAIDS, 2006