Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AF095 | 05AF095 | Afghanistan | 2005 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M, I93L |
| >05AF095| codons 1-99 PQITLWQRPLVTVKIGGQQREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6N, K11R, V35T, V60I, K122E, I135T, D177E, G196S, T200I, Q207A, R211K, V245E, D250E, A272P, I274V, K277R, E291D, V292I, I293V, I309L, G335D, R356K, M357K, G359S, A371V, I375V, A376T, T377L, T386I, K390R, T403M, E404D, E432D, D471E, Q480H, L491S, S519N, Q524K, I526V, K527E, E529D, A534S, A554T |
| >05AF095| codons 1-560 PISPINTVPVRLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEISQHRIKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGVKVRQLCKLLRGTKALTDIVPLTEEAE LELAENRELLKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVKQLTEVVQKVTLESIVIWGKIPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEKLVEKDKVYLSWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Sanders-Buell, E | A nascent HIV type 1 epidemic among injecting drug users in Kabul, Afghanistan is dominated by complex AD recombinant strain, CRF35_AD. | ARHR, 2007 |