Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1013 | 1013-03 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, K34R, G59E, I72V, L101I, T112A, T124A, T125A, A133T | Q285P |
| >1013-03| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAREIVASCDKCQLKGEAMHGQVDCSPEI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKAIHTDNGSN FTSAAVKAACWWTGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRPDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63P, C67Y |
| >1013-03| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEIYGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, S162A, E248D, K281R, I293V, G333E, Q367L, K390R, E399D, A400T, V435M, V467I, A554T, I556V |
| >1013-03| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKLLTEAVQKIATESIVIWGKTPKFRLPIQKETWDTWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIMGAETFYVDGAANRETKLGKAGYVTDRGRQKVISLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGVRKVL |
References
| Author | Title | Citation |
| Bernardin, F | Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes. | J Virol, 2005 |