Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PS1044 | 1044_d0 | Australia | 2004 | HIV1 | A | PBMC | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, A21T, V31I, V32I, S39C, I72V, T112V, I113V, T124A, T125A, G134N, K136Q, D167E, V201I, Q216H, L234I, S255T | S283G |
| >1044_d0| codons 1-288 FLDGIDKAQEDHERYHSNWRTMASDFNLPPIIAKEIVACCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKHITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNTDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | L10I, I13V, K14R, G16E, K20R, E35D, M36I, N37D, R41K, K45R, R57K, L63S, H69K, K70R, L89M |
| >1044_d0| codons 1-99 PQITLWQRPIVTVRIEGQLREALLDTGADDTVLEDIDLPGKWKPRMIGGIGGFIKVKQYD QISIEICGKRAIGTVLVGPTPVNIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E28A, V35T, E40D, V60I, K122E, D123N, I135T, F171Y, K173A, Q174K, V179I, T200A, Q207A, R211S, V245N, D250E, T286A, E291D, I293V, P294T, D324E, G335D, M357K, G359S, H361HY, K366R, T369A, A371V, I375V, A376V, T377M, E399D, A400T, T403M, E404D, E432D, V467I, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, K558R |
| >1044_d0| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICTDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPYRAKNPDIII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPINLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA YTNDVRQLAEVVQKVVMESIVIWGKTPKFKLPIQKETWDTWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVISLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRRVL |
References
| Author | Title | Citation |
| Li, B | Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution. | J Virol, 2007 |