Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 110PA | 110PA | Brazil | 2002 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36I, N37E, R41N, D60N, L63P, H69K, L89M, I93L |
| >110PA| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEIELPGNWKPKMIGGIGGFIKVRQYN QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39D, S48E, D123S, K166R, D177E, I178V, R211K, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377L, V381I, K390R, K395R, E404D, V435I, V466S, D471E, H483Q, L491S, S519N, K530R, A534S, A554K |
| >110PA| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKSFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEVVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIALESIIIWGKTPKFRLPIQRETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKSVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSKGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, M50T, L101I, K111R, T112V, T124N, K136Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A | V281M |
| >110PA| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVRVIHTDNGSN FTSNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCMASRQDED |
References
| Author | Title | Citation |
| Santos, AF | Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. | AIDS, 2006 |