Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 1579A | 1579A | India | 2001 | HIV1 | C | PBMC | BC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, N37D, P39S, R41K, R57K, I62V, H69K, K70R, L89M |
| >1579A| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDIDLSGKWKPKMIGGIGGFIKVKQYD QVLIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, V60I, I135V, S162N, K173A, D177E, I195T, Q197K, T200A, Q207E, E224G, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, V317A, D324E, Q334H, G335D, R356K, G359T, T369A, T377M, K390R, A400T, E404D, V435A, V466I, D471E, T473P, H483Y, L491S, T497P, S519N, A534S, A554S |
| >1579A| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLETGKHRAKIEELREHLLRWGFTTPDKKHQKGPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKELIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLTETPNQKTELQ AIYLALQDSGSEVNIVPDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L74M | V31I, M50I, I72V, P90Q, L101I, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, I203M, K219R | S283G |
| >1579A| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVIMVAVHVASGYIEAEVIQAETGQETAYFILKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITRIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Rodriguez, MA | Construction and characterization of an infectious molecular clone of HIV-1 subtype A of Indian origin. | Virology, 2006 |