Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 04BR142 | 04BR142 | Brazil | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI + RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, M36I, N37K, R41N, H69K, L89M, I93L |
| >04BR142| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215D | K103N | V35T, T39N, K43R, K122E, D123S, R211K, V245E, E248D, D250E, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, K366R, A376T, T377L, K390R, K395R, A400T, E404D, L452M, V466C, D471E, H483Q, L491S, S519N, Q524L, K527N, K530R, A534S, A554N |
| >04BR142| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEREGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFDTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKITLESIVIWGKTPKFRLPIQRETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKMGKAGYVTDRGRQKCVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIELLINKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50T, L101I, T112V, T124N, K136Q, V201I, L234I, I251L, A265V, R269K, D278A | V281M |
| >04BR142| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCMASRQDED |
References
| Author | Title | Citation |
| Sanabani, S | Full-length genome analysis of human immunodeficiency virus type 1 subtype C in Brazil. | ARHR, 2006 |