Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 04BR137 | 04BR137 | Brazil | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI + RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, N37K, R41N, H69K, L89I, I93L |
| >04BR137| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMKLPGNWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39D, K122E, D123N, I135T, R211K, V245Q, A272S, T286A, E291D, V292I, I293V, V317A, I329L, G335D, R356K, G359T, K366R, T377L, T386V, K390R, E404D, V435A, L452M, V466I, D471E, H483Q, L491S, S519N, K527R, K530R, A534S, A554N |
| >04BR137| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIALESIVIWGKVPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDRGRQKIVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, D25E, K34R, M50T, A91T, L101I, T112V, S119P, T122I, T124N, K136Q, V201I, L234I, I251L, D278A | V281M, S283G |
| >04BR137| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMASEFNLPPVVAREIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPTETGQETAYFILKLAGRWPVKVIHTDNGPN FISNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVLQDNSDIKVVPRRKAKIIRDYGKQMAGADCMAGRQDED |
References
| Author | Title | Citation |
| Sanabani, S | Full-length genome analysis of human immunodeficiency virus type 1 subtype C in Brazil. | ARHR, 2006 |