<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GHNJ188 GHNJ188 Ghana 2004 HIV1 CRF02_AG PBMC BC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, L19P, K20I, M36I, R41K, H69K, K70R, L89I  
>GHNJ188| codons 1-99
PQITLWQRPLVTVRIGGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  K70Q     V35T, E36D, T39N, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, V245Q, K281R, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357K, G359S, A371V, I375A, V381I, K390R, Q394P, K395R, T403M, E432D, V435I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554N, K558R T253A
>GHNJ188| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWAVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKAATESIIIWGKTPKFRLPIPRETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK
GIGGNEQVDKLVSNGIRRVL

References
Author Title Citation
Tatsumi, M Infectious DNA clones of subtype G and CRF02_AG HIV-1 derived from Ghananian isolates. Direct Genbank Submission, 2006