<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DDJ364 DDJ364 Senegal 1996 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, R41K, H69K, K70R, V82I, L89M  
>DDJ364| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11T, V35T, E36D, K122E, D123S, I135T, I142V, S162A, K173S, D177E, Q207A, R211K, V245E, E248D, D250E, T286A, E291D, V292I, I293V, P294I, E312N, I326V, G335D, A355T, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410Y, E432D, S468P, D471E, Q480Y, L491S, E492T, K512R, L517I, S519N, Q524K, K527E, K530R, A534S, A554S  
>DDJ364| codons 1-560
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRSQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVILTEEAE
LELAENREILKNPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYTRKRSA
HTNDVRQLVEVVQKVVTESIVIWGKTPKFKLPIQKETWETWWMEYWQATYIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELY
AIHLALQDSGSTVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T218I, L234I, A265V S283G
>DDJ364| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Meloni, ST Distinct human immunodeficiency virus type 1 subtype A virus circulating in West Africa: Sub-subtype A3. J Virol, 2004