Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CO6770 | CO6770 | Tanzania | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I15V, M36I, N37K, R41N, K45R, C67S, H69K, L89M, I93L |
| >CO6770| codons 1-99 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEIKLPGNWKPRMIGGIGGFIKVRQYD QILIEISGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K22R, V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, E194N, T200A, Q207E, V245Q, E248D, D250G, A272K, K277R, T286A, E291D, V292I, I293V, D324E, G335D, P345Q, F346H, R356K, G359T, T377Q, K390R, A400I, E404D, V435A, L452M, R461K, V466I, D471E, K476R, H483K, Q487E, L491S, L517I, S519N, K530R, A534S, A554S |
| >CO6770| codons 1-560 PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLNIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKGSWTVNDIQKLVGKLNWASQIYKGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEQHKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDKGRQKIVSLTETTNQRTELQ AIKLALEDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6E, V31I, V37I, M50I, I84M, L101I, T112V, S119T, T124S, T125A, K136Q, V201I, Q216R, T218L, K219Q, L234I, R269K, D278A |
| >CO6770| codons 1-288 FLDGIEKAQEEHEKYHSNWRAMASDFNLPPIVAKEIIASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGTN FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKRILQIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVASRQDED |
References
| Author | Title | Citation |
| Arroyo, MA | HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania. | AIDS, 2005 |