<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
02BR034 02BR034 Brazil 2002 HIV1 F PBMC None

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89M  
>02BR034| codons 1-99
PQITLWQRPLVTIKIEGQLMEALLDTGADDTVLEDVNLPGKWRPKMIGGIGGFIKVKQYD
NILIEICGHKAIGTVLVGPTPVNIIGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181C   E6R, V35T, T39L, V90I, V118I, K122E, S162C, E169D, K173T, Q174K, T200A, Q207E, R211K, F214L, H221Y, L228H, V245Q, E248D, A272P, T286A, V292I, I293V, E297A, R356K, G359S, T377L, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452K, V466A, D471E, T477A, H483Q, L491S, E492K, A502V, E514D, S519N, K527E, A534S  
>02BR034| codons 1-560
PISPIRTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKYQKEPPFHWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPILKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGASNRETKKGKAGYVTDRGRQKAVSLTETTNQKAELQ
AIQLALQDSGSKVNIVTDSQYVLGIIQAQPDKSDSELVNQIIEQLIEKEKVYLSWVPAHK
GIGGNEQVDKLVSAGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  V151I S17N, A21S, L101I, T112I, V201I, L234V, D256E S283G, R284G
>02BR034| codons 1-288
FLDGIDKAQEEHEKYHNNWRSMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKIIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGGQDED

References
Author Title Citation
Sanabani, S Analysis of the near full length genomes of HIV-1 subtypes B, F and BF recombinant from a cohort of 14 patients in Sao Paulo, Brazil. Infect Genet Evol, 2006