Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KNH1268 | KNH1268 | Kenya | 2000 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37K, R41N, L63P, H69K, V82I, L89M, I93L |
| >KNH1268| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, E40D, S48T, K122E, I135T, K173T, D177E, T200A, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E297D, G335D, F346Y, R356K, M357L, G359T, T377Q, K385R, K390R, A400T, T403S, E404D, L452M, R461K, V466I, T470N, D471E, Q480H, H483K, L491S, S519N, K530R, A534S, A554S |
| >KNH1268| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTDEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPYKNLKTGKYAKLRTA HTNDVKQLTEAVQKIAQESIVIWGRTPKFRLPIQKETWETWWSDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKMGKAGYVTDKGRQKIVSLNETTNQKTELH AIKLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E13D, S17N, M50T, I72T, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, K188R, V201I, K211R, T218I, L234I, A265V, R269K, D278A | S283G |
| >KNH1268| codons 1-288 FLDGIDKAQEEHDKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKTILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSSAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRRGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Visawapoka, U | Circulating and unique recombinant forms of HIV Type 1 containing subsubtype A2. | ARHR, 2006 |