Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KNH1271 | KNH1271 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, G16E, E35D, M36I, P39S, R41K, K43R, L63T, G68E, H69K, K70R, L89M, T91V |
| >KNH1271| codons 1-99 PQITLWQRPVVTVRIEGQLKEALLDTGADDTVLEDINLSGKWRPKMIGGIGGFIKVRQYD QITIEICEKRAIGTVLVGPTPVNIIGRNMLVQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I2V, P4T, V35T, T39K, K43E, D121H, K122E, I135T, D177E, Q207E, R211K, V245E, A272G, K277R, K281R, E291D, V292I, I293V, E297R, A304E, E312N, D324E, G335D, R356K, M357K, G359S, A360T, T377M, K390R, A400T, Y405H, T409N, V435A, R463K, V466I, D471E, K476R, Q480H, H483Y, L491V, K512R, E514D, S519N, Q524K, K527E, K530R, A534S, V548I, A554S |
| >KNH1271| codons 1-560 PVSTIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYGGIKVRQLCRLLRGTKALTDIVPLTREAE LELEENREILKNPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRST HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWTEHWQANWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGKQKIVSLTETTNQRTELH AIYLALQDSGVEVNIVTDSQYALGIIQAQPDRSDSELVNQIIEKLIEKERVYLSWVPAHK GIGGNEQIDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24H, L28I, S39C, L45I, M50I, I72V, L101I, T112V, S119P, T124A, K136Q, D167E, K215R, L234I | S283G |
| >KNH1271| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMAHDFNIPPVVAKEIVACCDKCQIKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN FTSATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQRQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Visawapoka, U | Circulating and unique recombinant forms of HIV Type 1 containing subsubtype A2. | ARHR, 2006 |