Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA25655 | CA84315 | U.S. | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
| 2 | Unknown | 52 |
| 3 | FPV+FTC+RTV | 74 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML, I54V, V82C, L90M | L10F, L33F, G73S, L89V | I13IV, N37S, R41K, K43R, K55R, R57K, I62V, L63P, I64IM, A71V, I93L |
| >CA84315| codons 1-99 PQITLWQRPFVTVKIGGQLKEALLDTGADDTVFEEMSLPGKWRPKLIGGIGGFVRVKQYD QVPMEICGHKVISTVLVGPTPCNIIGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67N, M184V, L210W, T215Y | K219KE | K103N | K20R, T39TAEK, E40EK, K43KN, V60I, V118I, I142IV, Q174N, D177DN, V179VI, D192DN, G196E, E203A, Q207E, R211K, E224D, L228H, A272P, K277R, I293IV, P294T |
| >CA84316| codons 1-302 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICKKLENEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPNIII YQYVDDLYVGSNLEIEQHRTKIAELREHLWKWGFYTPDEKHQKDPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVTLTEEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |