<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA23800 CA84293 U.S. 2007 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 22
2 3TC+AZT+IDV 78
3 3TC+D4T+NFV 96
4 ABC+APV+EFV+RTV 52
5 3TC+ABC+AZT+LPV 13
6 3TC+ABC+AZT 85
7 3TC+ABC+AZT+EFV 24
8 3TC+AZT+EFV+TDF 57
9 ATV+D4T+RTV+TDF 39
10 ATV+DDI+FTC+RTV+TDF 103

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I50L, V82T, L90M   L10R, N37H, R41K, L63P, A71L, I72V, V75VI, V77I, I93L  
>CA84293| codons 1-99
PQITLWQRPRVTIKIGGQLKEALLDTGADDTILEEMHLPGKWKPKIVGGLGGFIKVRQYD
QIPIEICGHKLVGTILIGPTPTNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E     P4PS, K20R, D123E, S162D, D177E, Q207E, R211RK, A272P, K277R, L283I, R284K, I293V, E297K  
>CA84294| codons 1-302
PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTEVVPLTKEAE
LE

References
Author Title Citation
Rhee, SY Predictive value of HIV-1 genotypic resistance test interpretation algorithms. J Infect Dis, 2009