Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1846 | CA8428 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 30 |
| 2 | AZT+D4T | 52 |
| 3 | AZT+DDI | 22 |
| 4 | 3TC+AZT+DDI+SQV | 13 |
| 5 | D4T+IDV | 17 |
| 6 | 3TC+D4T+IDV | 70 |
| 7 | DDI+NFV+NVP | 35 |
| 8 | 3TC+D4T+RTV+SQV | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L10F | K20I, E35D, M36I, L63P, A71V, I72T |
| >CA8428| codons 1-99 PQITLWQRPFVTIKIGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVTGTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |