Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1588 | CA8423 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ DLV | 20 |
| 2 | 3TC+ D4T+ SQV | 15 |
| 3 | 3TC+ AZT+ IDV | 97 |
| 4 | D4T+DDI+NVP+RTV+SQV | 8 |
| 5 | D4T+DDI+NFV+SQV | 38 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I, F53L | L10I, R41K, K55KR, I62V, L63P, I64V, T74S, I93L |
| >CA8423| codons 1-99 PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGKWKPKIIGGIGGLVRVRQYD QVPVEICGHKAIGSVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |