Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7118 | CA84197 | U.S. | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+RTV+SQV | 78 |
| 2 | D4T+DDI+EFV | 104 |
| 3 | APV+DDI+LPV+RTV | 216 |
| 4 | ATV+FTC+RTV+TDF | 91 |
| 5 | DRV+FTC+RTV+T20+TDF | 25 |
| 6 | DRV+FTC+RTV+TDF | 21 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54M, I84V, L90M | L10F, V11I, L33F, G73A | I13V, G16A, L19LV, E34Q, K43I, G51A, L63P, I64M, C67Y, A71V, I72M |
| >CA84197| codons 1-99 PQITLWQRPFITVKIAGQVKEALLDTGADDTVFQEMNLPGRWIPKLIGGIAGFMKVRQYD QIPMEIYGHKVMATVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_SS, M184V, T215Y | A62V, D67EK | Y188L | V35L, A98S, V106I, K122E, D123DN, I135T, V189I, T200A, L228H, T286A, E297R |
| >CA84198| codons 2-301 ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPVF VIKKKKSSKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSITVLDVGDAYFSVPLD ENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY QYVDDLLIGSDLEIGQHRAKIEELRQHLLRWGFYTPDKKHQKEPPFHWMGYELHPDKWTV QPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTREAEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |