Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6602 | CA84187 | U.S. | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | ABC+EFV | 65 |
| 3 | APV+LPV+TDF | 209 |
| 4 | FPV+LPV+TDF | 93 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82F, L90M | L33F, K43T, G73AT | L10I, I13V, K20R, E35D, M36I, N37E, R57K, D60E, Q61E, I62V, L63P, I64IV, G68E, A71T, I72T, I93L |
| >CA84187| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADDTVFEDIELPGRWTPKIIGGIGGFVKVKQYE EVPVEICEHKTTTTVLVGPTPFNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | A62V, K70N | V35I, A98S, K122E, D123DN, E138Q, S162C, E169D, I178L, T200A, I202IV, R211K, L228R, I257L, A272P, K277R, T286A, A288S, I293V, T296S, E297R |
| >CA84188| codons 2-324 ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPVF VIKKKDSTNWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPLD ENFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDLVIY QYMDDLYVGSDLEIGQHRAKVEELRQHLLKWGFYTPDKKHQKEPPFRWMGYELHPDKWTV QPIVLPEKDSWTVNDLQKLVGKLNWASQIYPGIKVRQLCKLLRGAKSLTEVVPLSREAEL ELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |