<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
474 CS_474 Cote d'Ivoire 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|D4T|DDI|EFV|IDV|NFV 177

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11VI L10V, T12PQ, I13V, K14IR, I15IV, G16E, L19P, K20I, M36I, R41K, K43KR, L63LH, H69K, K70KR, I72IT, L89M  
>CS_474| codons 1-99
PQITLWQRPVIQVRVEGQPIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QIHIEICGKRATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I5V, V35T, E36D, V60VI, K122E, D123S, I135V, A158AS, S162A, K173S, Q174K, V179I, G196GE, T200A, I202V, Q207A, R211RS, V245Q E6EDHQ
>CS_474| codons 1-247
PISPVQTVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRSKNPDIII
YQYMDDLYVGSDLEIEQHRAKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLP

References
Author Title Citation
Seyler, C Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa. AIDS, 2007