<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
282 CS_282 Cote d'Ivoire 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|D4T|DDI|IDV|NFV 150

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M L89V L10V, T12TK, I13V, L19P, K20I, E35G, M36I, N37ND, Y59YC, L63P, E65EK, H69K, K70R, A71T  
>CS_282| codons 1-99
PQITLWQRPVVKVKIGGQPIEALLDTGADDTVLEGIDLPGRWKPKMIGGIGGFIKVRQCD
QIPIKICGKRTIGTVLVGPTPVNIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, T215Y       V35T, E36ED, T39TK, K43KE, V60I, I135L, S162A, K173I, Q174K, I178L, G196E, T200A, Q207E, V245Q V8VM
>CS_282| codons 1-267
PISPIETMPVKLKPGMDGPKVKQWPLTEEKIKALTDICKELEEEGKISKIGPENPYNTPI
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPDLVI
YQYVDDLYVGSDLEIEQHRAKIEELREHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWA

References
Author Title Citation
Seyler, C Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa. AIDS, 2007