<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
145 CS_145 Cote d'Ivoire 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 D4T|DDI|IDV 101

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90LM   I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70KR, L89M  
>CS_145| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, D121DH, K122E, I135V, A158AS, S162A, T165TI, E169K, K173T, Q174N, D177E, I178M, E194K, T200A, E203EG, R206K, Q207E, R211N, W212G, F214I, T216TP, D218N, Q242H, I244K, V245Q, E248K, D250N Q222P, L234LP, W239G
>CS_145| codons 1-250
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPSIFQASMIKILKPFRTNNPEMVI
YQYMDDLYVGSDLKIGQHRAKIGELKEHLLNGGITPPNKKHPKEPPFLWMGYEPHPDKGT
VHPKQLPKKN

References
Author Title Citation
Seyler, C Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa. AIDS, 2007