<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
027 CS_027 Cote d'Ivoire 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|NFV 165

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LV, I13V, K20I, M36I, R41K, I64V, H69K, T74S, L89M, I93M  
>CS_027| codons 1-99
PQITLWQRPVVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILVEICGKKAIGSVLVGPTPVNIIGRNMLTQMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V, T215SY       V21VI, V35T, E36D, T39A, W88C, V118I, K122E, I135R, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, F214L, V245Q, Y271F, T286A, E291D, I293V, S322T, I326V E79EK
>CS_027| codons 1-334
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTDICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRKLNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGLYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIFAGIKVKQLCKLLRGAKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

References
Author Title Citation
Seyler, C Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa. AIDS, 2007