Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| NV_KTB035 | 02.KTB035 | DRC | 2002 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| T97A, A128T | K7E, E10A, S17N, V31I, I72V, I84M, L101I, T112V, T125A, I135V, K136Q, V201I, I217V, T218L, L234I, D256E, D279G | S283G |
| >02.KTB035| codons 1-288 FLDGIDEAQAEHEKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQEAAYFILKLAGRWPVKVIHTDNGSN FTSTAVKTACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQVLKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDGCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, E35D, M36I, N37D, R41K, H69K, L89M |
| >02.KTB035| codons 1-99 PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V21I, T27S, V35T, T39R, V60I, K122E, D123N, I135T, S162C, K173S, Q207N, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, V317E, I326V, Q334H, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377V, K390R, T403M, E404D, E432D, D471E, Q480H, H483Y, K512R, L517I, S519N, Q524K, K527E, V531I, A534S, Q547K, A554S |
| >02.KTB035| codons 1-560 PISPIETVPVKLKPGMDGPKIKQWPLSEEKIKALTEICREMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGEYYDPSKDLVAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEVVQKVAVESIVIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGLEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKEKIYLSWVPAHK GIGGNEKVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Vidal, N | Identification and molecular characterization of subsubtype A4 in central Africa. | ARHR, 2006 |